Ribosomal protein uL3-like (RPL3L)

About Ribosomal protein uL3-like

Ribosomal protein uL3-like (RPL3L) is a protein from Homo sapiens identified by UniProt accession Q92901, 407 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Ribosomal protein uL3-like
UniProt accession	Q92901
Gene	RPL3L
Organism	Homo sapiens
Length	407 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

dilated cardiomyopathy · score 0.59
influenza · score 0.46
atrial fibrillation · score 0.45
familial isolated dilated cardiomyopathy · score 0.37
atrial flutter · score 0.36
creatinine measurement · score 0.34
clear cell renal carcinoma · score 0.27
endometrial cancer · score 0.27
glomerular filtration rate · score 0.27
Dilated cardiomyopathy · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92901-F1	alphafold	PREDICTED	94.70	—

Amino-acid sequence (407 residues)

MSHRKFSAPR HGHLGFLPHK RSHRHRGKVK TWPRDDPSQP VHLTAFLGYK AGMTHTLREV HRPGLKISKR EEVEAVTIVE TPPLVVVGVV GYVATPRGLR SFKTIFAEHL SDECRRRFYK DWHKSKKKAF TKACKRWRDT DGKKQLQKDF AAMKKYCKVI RVIVHTQMKL LPFRQKKAHI MEIQLNGGTV AEKVAWAQAR LEKQVPVHSV FSQSEVIDVI AVTKGRGVKG VTSRWHTKKL PRKTHKGLRK VACIGAWHPA RVGCSIARAG QKGYHHRTEL NKKIFRIGRG PHMEDGKLVK NNASTSYDVT AKSITPLGGF PHYGEVNNDF VMLKGCIAGT KKRVITLRKS LLVHHSRQAV ENIELKFIDT TSKFGHGRFQ TAQEKRAFMG PQKKHLEKET PETSGDL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards