About Fibroblast growth factor 13
Fibroblast growth factor 13 (FGF13) is a protein
from Homo sapiens identified by UniProt accession
Q92913, 245 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | Fibroblast growth factor 13 |
|---|
| UniProt accession | Q92913 |
|---|
| Gene | FGF13 |
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| Organism | Homo sapiens |
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| Length | 245 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- developmental and epileptic encephalopathy, 90 · score 0.69
- Intellectual disability · score 0.42
- developmental and epileptic encephalopathy · score 0.42
- Neurodevelopmental disorder · score 0.40
- Generalized epilepsy with febrile seizures-plus · score 0.37
- breast adenocarcinoma · score 0.24
- neurodegenerative disease · score 0.21
- genetic disorder · score 0.15
- endometrial cancer · score 0.10
- glioblastoma multiforme · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92913-F1 | alphafold | PREDICTED | 79.36 | — |
Amino-acid sequence (245 residues)
MAAAIASSLI RQKRQARERE KSNACKCVSS PSKGKTSCDK NKLNVFSRVK LFGSKKRRRR RPEPQLKGIV TKLYSRQGYH LQLQADGTID GTKDEDSTYT LFNLIPVGLR VVAIQGVQTK LYLAMNSEGY LYTSELFTPE CKFKESVFEN YYVTYSSMIY RQQQSGRGWY LGLNKEGEIM KGNHVKKNKP AAHFLPKPLK VAMYKEPSLH DLTEFSRSGS GTPTKSRSVS GVLNGGKSMS HNEST
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