Fibroblast growth factor 11 (FGF11)

Homo sapiens — UniProt Q92914

Gene: FGF11Homo sapiensSwissProt reviewed

About Fibroblast growth factor 11

Fibroblast growth factor 11 (FGF11) is a protein from Homo sapiens identified by UniProt accession Q92914, 225 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.

Target properties

Protein nameFibroblast growth factor 11
UniProt accessionQ92914
GeneFGF11
OrganismHomo sapiens
Length225 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (72)

Diseases linked to this target (Open Targets).

  • breast adenocarcinoma · score 0.24
  • genetic disorder · score 0.12
  • gastric adenocarcinoma · score 0.10
  • non-small cell lung carcinoma · score 0.10
  • balding measurement · score 0.09
  • puberty onset measurement · score 0.09
  • neoplasm · score 0.08
  • lung adenocarcinoma · score 0.07
  • papillary thyroid carcinoma · score 0.07
  • sex hormone-binding globulin measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q92914-F1alphafoldPREDICTED81.14—

Amino-acid sequence (225 residues)

MAALASSLIR QKREVREPGG SRPVSAQRRV CPRGTKSLCQ KQLLILLSKV RLCGGRPARP DRGPEPQLKG IVTKLFCRQG FYLQANPDGS IQGTPEDTSS FTHFNLIPVG LRVVTIQSAK LGHYMAMNAE GLLYSSPHFT AECRFKECVF ENYYVLYASA LYRQRRSGRA WYLGLDKEGQ VMKGNRVKKT KAAAHFLPKL LEVAMYQEPS LHSVPEASPS SPPAP

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Quick facts

UniProtQ92914
GeneFGF11
OrganismHomo sapiens
Length225
Binders0
Diseases72
View on UniProt