About Fibroblast growth factor 11
Fibroblast growth factor 11 (FGF11) is a protein
from Homo sapiens identified by UniProt accession
Q92914, 225 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Fibroblast growth factor 11 |
| UniProt accession | Q92914 |
| Gene | FGF11 |
| Organism | Homo sapiens |
| Length | 225 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.24
- genetic disorder · score 0.12
- gastric adenocarcinoma · score 0.10
- non-small cell lung carcinoma · score 0.10
- balding measurement · score 0.09
- puberty onset measurement · score 0.09
- neoplasm · score 0.08
- lung adenocarcinoma · score 0.07
- papillary thyroid carcinoma · score 0.07
- sex hormone-binding globulin measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q92914-F1 | alphafold | PREDICTED | 81.14 | — |
Amino-acid sequence (225 residues)
MAALASSLIR QKREVREPGG SRPVSAQRRV CPRGTKSLCQ KQLLILLSKV RLCGGRPARP DRGPEPQLKG IVTKLFCRQG FYLQANPDGS IQGTPEDTSS FTHFNLIPVG LRVVTIQSAK LGHYMAMNAE GLLYSSPHFT AECRFKECVF ENYYVLYASA LYRQRRSGRA WYLGLDKEGQ VMKGNRVKKT KAAAHFLPKL LEVAMYQEPS LHSVPEASPS SPPAP
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