About Ras-related protein Rab-8B
Ras-related protein Rab-8B (RAB8B) is a protein
from Homo sapiens identified by UniProt accession
Q92930, 207 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | Ras-related protein Rab-8B |
|---|
| UniProt accession | Q92930 |
|---|
| Gene | RAB8B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 207 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- cystatin C measurement · score 0.30
- creatinine measurement · score 0.30
- neurodegenerative disease · score 0.29
- mean corpuscular hemoglobin concentration · score 0.28
- serum metabolite measurement · score 0.26
- glomerular filtration rate · score 0.10
- serum urea measurement · score 0.08
- mean platelet volume · score 0.07
- infection · score 0.07
- infect · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92930-F1 | alphafold | PREDICTED | 86.58 | — |
Amino-acid sequence (207 residues)
MAKTYDYLFK LLLIGDSGVG KTCLLFRFSE DAFNTTFIST IGIDFKIRTI ELDGKKIKLQ IWDTAGQERF RTITTAYYRG AMGIMLVYDI TNEKSFDNIK NWIRNIEEHA SSDVERMILG NKCDMNDKRQ VSKERGEKLA IDYGIKFLET SAKSSANVEE AFFTLARDIM TKLNRKMNDS NSAGAGGPVK ITENRSKKTS FFRCSLL
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