About Homeobox protein DLX-4
Homeobox protein DLX-4 (DLX4) is a protein
from Homo sapiens identified by UniProt accession
Q92988, 240 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Homeobox protein DLX-4 |
|---|
| UniProt accession | Q92988 |
|---|
| Gene | DLX4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 240 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (72)
Diseases linked to this target (Open Targets).
- orofacial cleft 15 · score 0.48
- cleft lip/palate · score 0.37
- blood urea nitrogen measurement · score 0.30
- balding measurement · score 0.29
- hair color · score 0.23
- hair colour measurement · score 0.23
- serum urea measurement · score 0.20
- primary dental caries · score 0.19
- mean reticulocyte volume · score 0.12
- mean corpuscular volume · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92988-F1 | alphafold | PREDICTED | 65.60 | — |
Amino-acid sequence (240 residues)
MTSLPCPLPG RDASKAVFPD LAPVPSVAAA YPLGLSPTTA ASPNLSYSRP YGHLLSYPYT EPANPGDSYL SCQQPAALSQ PLCGPAEHPQ ELEADSEKPR LSPEPSERRP QAPAKKLRKP RTIYSSLQLQ HLNQRFQHTQ YLALPERAQL AAQLGLTQTQ VKIWFQNKRS KYKKLLKQNS GGQEGDFPGR TFSVSPCSPP LPSLWDLPKA GTLPTSGYGN SFGAWYQHHS SDVLASPQMM
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