Glomulin (GLMN)

About Glomulin

Glomulin (GLMN) is a protein from Homo sapiens identified by UniProt accession Q92990, 594 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

Target properties

Protein name	Glomulin
UniProt accession	Q92990
Gene	GLMN
Organism	Homo sapiens
Length	594 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (73)

Diseases linked to this target (Open Targets).

glomuvenous malformation · score 0.78
genetic disorder · score 0.41
blue rubber bleb nevus · score 0.37
myeloid white cell count · score 0.34
monocyte count · score 0.33
monocyte percentage of leukocytes · score 0.33
neurodegenerative disease · score 0.32
granulocyte percentage of myeloid white cells · score 0.32
lymphocyte percentage of leukocytes · score 0.30
lymphocyte count · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92990-F1	alphafold	PREDICTED	88.50	—

Amino-acid sequence (594 residues)

MAVEELQSII KRCQILEEQD FKEEDFGLFQ LAGQRCIEEG HTDQLLEIIQ NEKNKVIIKN MGWNLVGPVV RCLLCKDKED SKRKVYFLIF DLLVKLCNPK ELLLGLLELI EEPSGKQISQ SILLLLQPLQ TVIQKLHNKA YSIGLALSTL WNQLSLLPVP YSKEQIQMDD YGLCQCCKAL IEFTKPFVEE VIDNKENSLE NEKLKDELLK FCFKSLKCPL LTAQFFEQSE EGGNDPFRYF ASEIIGFLSA IGHPFPKMIF NHGRKKRTWN YLEFEEEENK QLADSMASLA YLVFVQGIHI DQLPMVLSPL YLLQFNMGHI EVFLQRTEES VISKGLELLE NSLLRIEDNS LLYQYLEIKS FLTVPQGLVK VMTLCPIETL RKKSLAMLQL YINKLDSQGK YTLFRCLLNT SNHSGVEAFI IQNIKNQIDM SLKRTRNNKW FTGPQLISLL DLVLFLPEGA ETDLLQNSDR IMASLNLLRY LVIKDNENDN QTGLWTELGN IENNFLKPLH IGLNMSKAHY EAEIKNSQEA QKSKDLCSIT VSGEEIPNMP PEMQLKVLHS ALFTFDLIES VLARVEELIE IKTKSTSEEN IGIK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards