About Stathmin-2
Stathmin-2 (STMN2) is a protein
from Homo sapiens identified by UniProt accession
Q93045, 179 residues long.
MolForge cross-references it against 0 known binders and
105 disease associations.
Target properties
| Protein name | Stathmin-2 |
|---|
| UniProt accession | Q93045 |
|---|
| Gene | STMN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 179 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (105)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- gut microbiome measurement · score 0.10
- axial length measurement · score 0.10
- Pick disease · score 0.07
- Barrett's esophagus · score 0.06
- schizophrenia · score 0.05
- intelligence · score 0.05
- self reported educational attainment · score 0.05
- ependymoma · score 0.05
- attention deficit hyperactivity disorder · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q93045-F1 | alphafold | PREDICTED | 85.63 | — |
Amino-acid sequence (179 residues)
MAKTAMAYKE KMKELSMLSL ICSCFYPEPR NINIYTYDDM EVKQINKRAS GQAFELILKP PSPISEAPRT LASPKKKDLS LEEIQKKLEA AEERRKSQEA QVLKQLAEKR EHEREVLQKA LEENNNFSKM AEEKLILKME QIKENREANL AAIIERLQEK ERHAAEVRRN KELQVELSG
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