Lipoma-preferred partner (LPP)

About Lipoma-preferred partner

Lipoma-preferred partner (LPP) is a protein from Homo sapiens identified by UniProt accession Q93052, 612 residues long. MolForge cross-references it against 0 known binders and 424 disease associations.

Target properties

Protein name	Lipoma-preferred partner
UniProt accession	Q93052
Gene	LPP
Organism	Homo sapiens
Length	612 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (424)

Diseases linked to this target (Open Targets).

acute myeloid leukemia · score 0.44
skin carcinoma · score 0.43
body height · score 0.41
body mass index · score 0.39
intraocular pressure measurement · score 0.38
asthma · score 0.38
celiac disease · score 0.38
prostate adenocarcinoma · score 0.37
pancreatic ductal adenocarcinoma · score 0.37
pancreatic carcinoma · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q93052-F1	alphafold	PREDICTED	60.38	—

Amino-acid sequence (612 residues)

MSHPSWLPPK STGEPLGHVP ARMETTHSFG NPSISVSTQQ PPKKFAPVVA PKPKYNPYKQ PGGEGDFLPP PPPPLDDSSA LPSISGNFPP PPPLDEEAFK VQGNPGGKTL EERRSSLDAE IDSLTSILAD LECSSPYKPR PPQSSTGSTA SPPVSTPVTG HKRMVIPNQP PLTATKKSTL KPQPAPQAGP IPVAPIGTLK PQPQPVPASY TTASTSSRPT FNVQVKSAQP SPHYMAAPSS GQIYGSGPQG YNTQPVPVSG QCPPPSTRGG MDYAYIPPPG LQPEPGYGYA PNQGRYYEGY YAAGPGYGGR NDSDPTYGQQ GHPNTWKREP GYTPPGAGNQ NPPGMYPVTG PKKTYITDPV SAPCAPPLQP KGGHSGQLGP SSVAPSFRPE DELEHLTKKM LYDMENPPAD EYFGRCARCG ENVVGEGTGC TAMDQVFHVD CFTCIICNNK LRGQPFYAVE KKAYCEPCYI NTLEQCNVCS KPIMERILRA TGKAYHPHCF TCVMCHRSLD GIPFTVDAGG LIHCIEDFHK KFAPRCSVCK EPIMPAPGQE ETVRIVALDR DFHVHCYRCE DCGGLLSEGD NQGCYPLDGH ILCKTCNSAR IRVLTAKAST DL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards