Histone H2A type 1-C (H2AC6)

About Histone H2A type 1-C

Histone H2A type 1-C (H2AC6) is a protein from Homo sapiens identified by UniProt accession Q93077, 130 residues long. MolForge cross-references it against 0 known binders and 109 disease associations.

Target properties

Protein name	Histone H2A type 1-C
UniProt accession	Q93077
Gene	H2AC6
Organism	Homo sapiens
Length	130 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (109)

Diseases linked to this target (Open Targets).

viral disease · score 0.50
infectious disease · score 0.50
breast carcinoma · score 0.37
cancer · score 0.37
melanoma · score 0.37
Red cell distribution width · score 0.27
mean corpuscular hemoglobin concentration · score 0.23
platelet count · score 0.22
schizophrenia · score 0.21
mean corpuscular volume · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q93077-F1	alphafold	PREDICTED	91.01	—

Amino-acid sequence (130 residues)

MSGRGKQGGK ARAKAKSRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YLAAVLEYLT AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGR VTIAQGGVLP NIQAVLLPKK TESHHKAKGK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards