Histone H2B type 1-H (H2BC9)

About Histone H2B type 1-H

Histone H2B type 1-H (H2BC9) is a protein from Homo sapiens identified by UniProt accession Q93079, 126 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Histone H2B type 1-H
UniProt accession	Q93079
Gene	H2BC9
Organism	Homo sapiens
Length	126 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

viral disease · score 0.50
infectious disease · score 0.50
breast carcinoma · score 0.38
cancer · score 0.37
melanoma · score 0.37
non-small cell lung carcinoma · score 0.05
central nervous system cancer · score 0.05
BMI-adjusted waist circumference · score 0.04
birth weight · score 0.03
parental genotype effect measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q93079-F1	alphafold	PREDICTED	87.99	—

Amino-acid sequence (126 residues)

MPDPAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSV YVYKVLKQVH PDTGISSKAM GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT KYTSSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards