About Ribonuclease K6
Ribonuclease K6 (RNASE6) is a protein
from Homo sapiens identified by UniProt accession
Q93091, 150 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Ribonuclease K6 |
|---|
| UniProt accession | Q93091 |
|---|
| Gene | RNASE6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 150 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (60)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.32
- endometrial cancer · score 0.15
- bacterial urinary tract infection · score 0.09
- visual perception measurement · score 0.04
- Acute hepatic failure · score 0.04
- chronic intestinal pseudoobstruction · score 0.03
- Congenital intrinsic factor deficiency · score 0.03
- neutropenia, severe congenital, 2, autosomal dominant · score 0.03
- 46,XX ovotesticular disorder of sex development · score 0.03
- pyelonephritis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q93091-F1 | alphafold | PREDICTED | 90.50 | — |
Amino-acid sequence (150 residues)
MVLCFPLLLL LLVLWGPVCP LHAWPKRLTK AHWFEIQHIQ PSPLQCNRAM SGINNYTQHC KHQNTFLHDS FQNVAAVCDL LSIVCKNRRH NCHQSSKPVN MTDCRLTSGK YPQCRYSAAA QYKFFIVACD PPQKSDPPYK LVPVHLDSIL
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