Protein Wnt-2b (WNT2B)

About Protein Wnt-2b

Protein Wnt-2b (WNT2B) is a protein from Homo sapiens identified by UniProt accession Q93097, 391 residues long. MolForge cross-references it against 0 known binders and 197 disease associations.

Target properties

Protein name	Protein Wnt-2b
UniProt accession	Q93097
Gene	WNT2B
Organism	Homo sapiens
Length	391 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (197)

Diseases linked to this target (Open Targets).

Diarrhea, Infantile · score 0.56
systolic blood pressure · score 0.47
diastolic blood pressure · score 0.47
hypertension · score 0.46
smoking status measurement · score 0.45
heel bone mineral density · score 0.44
mean arterial pressure · score 0.43
Calcium channel blocker use measurement · score 0.40
testosterone measurement · score 0.39
cardiovascular disease · score 0.38

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q93097-F1	alphafold	PREDICTED	86.33	—

Amino-acid sequence (391 residues)

MLRPGGAEEA AQLPLRRASA PVPVPSPAAP DGSRASARLG LACLLLLLLL TLPARVDTSW WYIGALGARV ICDNIPGLVS RQRQLCQRYP DIMRSVGEGA REWIRECQHQ FRHHRWNCTT LDRDHTVFGR VMLRSSREAA FVYAISSAGV VHAITRACSQ GELSVCSCDP YTRGRHHDQR GDFDWGGCSD NIHYGVRFAK AFVDAKEKRL KDARALMNLH NNRCGRTAVR RFLKLECKCH GVSGSCTLRT CWRALSDFRR TGDYLRRRYD GAVQVMATQD GANFTAARQG YRRATRTDLV YFDNSPDYCV LDKAAGSLGT AGRVCSKTSK GTDGCEIMCC GRGYDTTRVT RVTQCECKFH WCCAVRCKEC RNTVDVHTCK APKKAEWLDQ T

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards