About Protein Wnt-8b
Protein Wnt-8b (WNT8B) is a protein
from Homo sapiens identified by UniProt accession
Q93098, 351 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Protein Wnt-8b |
|---|
| UniProt accession | Q93098 |
|---|
| Gene | WNT8B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 351 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- endometrial cancer · score 0.18
- diet measurement · score 0.17
- palmitoleic acid measurement · score 0.11
- lung adenocarcinoma · score 0.10
- hepatocellular carcinoma · score 0.08
- fatty acid measurement · score 0.07
- alkaline phosphatase measurement · score 0.05
- body mass index · score 0.05
- neoplasm · score 0.04
- t-tau:beta-amyloid 1-42 ratio measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q93098-F1 | alphafold | PREDICTED | 84.56 | — |
Amino-acid sequence (351 residues)
MFLSKPSVYI CLFTCVLQLS HSWSVNNFLM TGPKAYLIYS SSVAAGAQSG IEECKYQFAW DRWNCPERAL QLSSHGGLRS ANRETAFVHA ISSAGVMYTL TRNCSLGDFD NCGCDDSRNG QLGGQGWLWG GCSDNVGFGE AISKQFVDAL ETGQDARAAM NLHNNEAGRK AVKGTMKRTC KCHGVSGSCT TQTCWLQLPE FREVGAHLKE KYHAALKVDL LQGAGNSAAG RGAIADTFRS ISTRELVHLE DSPDYCLENK TLGLLGTEGR ECLRRGRALG RWERRSCRRL CGDCGLAVEE RRAETVSSCN CKFHWCCAVR CEQCRRRVTK YFCSRAERPR GGAAHKPGRK P
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