Major histocompatibility complex class I-related protein 1 (MR1)

About Major histocompatibility complex class I-related protein 1

Major histocompatibility complex class I-related protein 1 (MR1) is a protein from Homo sapiens identified by UniProt accession Q95460, 341 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.

Target properties

Protein name	Major histocompatibility complex class I-related protein 1
UniProt accession	Q95460
Gene	MR1
Organism	Homo sapiens
Length	341 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q95460-F1	alphafold	PREDICTED	87.48	—

Amino-acid sequence (341 residues)

MGELMAFLLP LIIVLMVKHS DSRTHSLRYF RLGVSDPIHG VPEFISVGYV DSHPITTYDS VTRQKEPRAP WMAENLAPDH WERYTQLLRG WQQMFKVELK RLQRHYNHSG SHTYQRMIGC ELLEDGSTTG FLQYAYDGQD FLIFNKDTLS WLAVDNVAHT IKQAWEANQH ELLYQKNWLE EECIAWLKRF LEYGKDTLQR TEPPLVRVNR KETFPGVTAL FCKAHGFYPP EIYMTWMKNG EEIVQEIDYG DILPSGDGTY QAWASIELDP QSSNLYSCHV EHCGVHMVLQ VPQESETIPL VMKAVSGSIV LVIVLAGVGV LVWRRRPREQ NGAIYLPTPD R

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards