About Secretory carrier-associated membrane protein 4
Secretory carrier-associated membrane protein 4 (SCAMP4) is a protein
from Homo sapiens identified by UniProt accession
Q969E2, 229 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Secretory carrier-associated membrane protein 4 |
|---|
| UniProt accession | Q969E2 |
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| Gene | SCAMP4 |
|---|
| Organism | Homo sapiens |
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| Length | 229 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- intellectual disability-strabismus syndrome · score 0.49
- genetic disorder · score 0.19
- Microcephaly · score 0.11
- reticulocyte count · score 0.03
- mean corpuscular volume · score 0.03
- body mass index · score 0.02
- psoriasis · score 0.02
- neoplasm · score 0.02
- glioblastoma multiforme · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969E2-F1 | alphafold | PREDICTED | 86.21 | — |
Amino-acid sequence (229 residues)
MSEKENNFPP LPKFIPVKPC FYQNFSDEIP VEHQVLVKRI YRLWMFYCAT LGVNLIACLA WWIGGGSGTN FGLAFVWLLL FTPCGYVCWF RPVYKAFRAD SSFNFMAFFF IFGAQFVLTV IQAIGFSGWG ACGWLSAIGF FQYSPGAAVV MLLPAIMFSV SAAMMAIAIM KVHRIYRGAG GSFQKAQTEW NTGTWRNPPS REAQYNNFSG NSLPEYPTVP SYPGSGQWP
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