Transcription elongation factor A protein-like 3…

About Transcription elongation factor A protein-like 3

Transcription elongation factor A protein-like 3 (TCEAL3) is a protein from Homo sapiens identified by UniProt accession Q969E4, 200 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Transcription elongation factor A protein-like 3
UniProt accession	Q969E4
Gene	TCEAL3
Organism	Homo sapiens
Length	200 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.47
ovarian carcinoma · score 0.02
large cell medulloblastoma · score 0.01
colorectal cancer · score 0.01
cancer · score 0.00
lung adenocarcinoma · score 0.00
vulvar intraepithelial neoplasia · score 0.00
hepatitis B virus induced hepatocellular carcinoma · score 0.00
myocardial infarction · score 0.00
hepatitis C virus induced hepatocellular carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969E4-F1	alphafold	PREDICTED	58.56	—

Amino-acid sequence (200 residues)

MEKPYNKNEG NLENEGKPED EVEPDDEGKS DEEEKPDVEG KTECEGKRED EGEPGDEGQL EDEGSQEKQG RSEGEGKPQG EGKPASQAKP ESQPRAAEKR PAEDYVPRKA KRKTDRGTDD SPKDSQEDLQ ERHLSSEEMM RECGDVSRAQ EELRKKQKMG GFHWMQRDVQ DPFAPRGQRG VRGVRGGGRG QRGLHDIPYL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Transcription elongation factor A protein-like 3 (TCEAL3)