Fetal and adult testis-expressed transcript protein…

About Fetal and adult testis-expressed transcript protein

Fetal and adult testis-expressed transcript protein (FATE1) is a protein from Homo sapiens identified by UniProt accession Q969F0, 183 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Fetal and adult testis-expressed transcript protein
UniProt accession	Q969F0
Gene	FATE1
Organism	Homo sapiens
Length	183 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

neoplasm · score 0.07
bone disease · score 0.05
cartilage disease · score 0.05
adrenal cortex carcinoma · score 0.05
adrenal cortex neoplasm · score 0.01
Infertility · score 0.01
cancer · score 0.01
hepatocellular carcinoma · score 0.00
osteosarcoma · score 0.00
sarcoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969F0-F1	alphafold	PREDICTED	63.67	—

Amino-acid sequence (183 residues)

MAGGPPNTKA EMEMSLAEEL NHGRQGENQE HLVIAEMMEL GSRSRGASQK KQKLEQKAAG SASAKRVWNM TATRPKKMGS QLPKPRMLRE SGHGDAHLQE YAGNFQGIRF HYDRNPGTDA VAQTSLEEFN VLEMEVMRRQ LYAVNRRLRA LEEQGATWRH RETLIIAVLV SASIANLWLW MNQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Fetal and adult testis-expressed transcript protein (FATE1)