Caveolae-associated protein 3 (CAVIN3)

About Caveolae-associated protein 3

Caveolae-associated protein 3 (CAVIN3) is a protein from Homo sapiens identified by UniProt accession Q969G5, 261 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.

Target properties

Protein name	Caveolae-associated protein 3
UniProt accession	Q969G5
Gene	CAVIN3
Organism	Homo sapiens
Length	261 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (120)

Diseases linked to this target (Open Targets).

gut microbiome measurement · score 0.18
neoplasm · score 0.09
breast cancer · score 0.09
Blackfan-Diamond anemia · score 0.08
cancer · score 0.07
hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.07
Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.06
alpha thalassemia-intellectual disability syndrome type 1 · score 0.06
beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.06
alpha-thalassemia-myelodysplastic syndrome · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969G5-F1	alphafold	PREDICTED	71.57	—

Amino-acid sequence (261 residues)

MRESALERGP VPEAPAGGPV HAVTVVTLLE KLASMLETLR ERQGGLARRQ GGLAGSVRRI QSGLGALSRS HDTTSNTLAQ LLAKAERVSS HANAAQERAV RRAAQVQRLE ANHGLLVARG KLHVLLFKEE GEVPASAFQK APEPLGPADQ SELGPEQLEA EVGESSDEEP VESRAQRLRR TGLQKVQSLR RALSGRKGPA APPPTPVKPP RLGPGRSAEA QPEAQPALEP TLEPEPPQDT EEDPGRPGAA EEALLQMESV A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards