About Ribonuclease P/MRP protein subunit POP5
Ribonuclease P/MRP protein subunit POP5 (POP5) is a protein
from Homo sapiens identified by UniProt accession
Q969H6, 163 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Ribonuclease P/MRP protein subunit POP5 |
|---|
| UniProt accession | Q969H6 |
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| Gene | POP5 |
|---|
| Organism | Homo sapiens |
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| Length | 163 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- mean corpuscular volume · score 0.21
- mean corpuscular hemoglobin concentration · score 0.14
- Red cell distribution width · score 0.14
- mean reticulocyte volume · score 0.13
- mathematical ability · score 0.12
- mean corpuscular hemoglobin · score 0.10
- chronotype measurement · score 0.10
- reticulocyte count · score 0.10
- self reported educational attainment · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969H6-F1 | alphafold | PREDICTED | 90.52 | — |
Amino-acid sequence (163 residues)
MVRFKHRYLL CELVSDDPRC RLSLDDRVLS SLVRDTIARV HGTFGAAACS IGFAVRYLNA YTGIVLLRCR KEFYQLVWSA LPFITYLENK GHRYPCFFNT LHVGGTIRTC QKFLIQYNRR QLLILLQNCT DEGEREAIQK SVTRSCLLEE EEESGEEAAE AME
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