Myeloid-derived growth factor (MYDGF)

About Myeloid-derived growth factor

Myeloid-derived growth factor (MYDGF) is a protein from Homo sapiens identified by UniProt accession Q969H8, 173 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.

Target properties

Protein name	Myeloid-derived growth factor
UniProt accession	Q969H8
Gene	MYDGF
Organism	Homo sapiens
Length	173 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (59)

Diseases linked to this target (Open Targets).

atherosclerosis · score 0.08
hepatocellular carcinoma · score 0.08
non-alcoholic fatty liver disease · score 0.08
breast cancer · score 0.07
neoplasm · score 0.07
diabetic nephropathy · score 0.03
myocardial infarction · score 0.03
urinary bladder carcinoma · score 0.03
Hepatic steatosis · score 0.03
allergic rhinitis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969H8-F1	alphafold	PREDICTED	87.84	—

Amino-acid sequence (173 residues)

MAAPSGGWNG VGASLWAALL LGAVALRPAE AVSEPTTVAF DVRPGGVVHS FSHNVGPGDK YTCMFTYASQ GGTNEQWQMS LGTSEDHQHF TCTIWRPQGK SYLYFTQFKA EVRGAEIEYA MAYSKAAFER ESDVPLKTEE FEVTKTAVAH RPGAFKAELS KLVIVAKASR TEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards