About Sodium-coupled neutral amino acid transporter 4
Sodium-coupled neutral amino acid transporter 4 (SLC38A4) is a protein
from Homo sapiens identified by UniProt accession
Q969I6, 547 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | Sodium-coupled neutral amino acid transporter 4 |
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| UniProt accession | Q969I6 |
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| Gene | SLC38A4 |
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| Organism | Homo sapiens |
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| Length | 547 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (63)
Diseases linked to this target (Open Targets).
- body height · score 0.47
- platelet count · score 0.43
- serum albumin measurement · score 0.40
- urate measurement · score 0.39
- C-reactive protein measurement · score 0.39
- birth weight · score 0.39
- serum alanine aminotransferase measurement · score 0.32
- cystatin C measurement · score 0.32
- triglyceride measurement · score 0.32
- IGF-1 measurement · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969I6-F1 | alphafold | PREDICTED | 75.48 | — |
Amino-acid sequence (547 residues)
MDPMELRNVN IEPDDESSSG ESAPDSYIGI GNSEKAAMSS QFANEDTESQ KFLTNGFLGK KKLADYADEH HPGTTSFGMS SFNLSNAIMG SGILGLSYAM ANTGIILFII MLLAVAILSL YSVHLLLKTA KEGGSLIYEK LGEKAFGWPG KIGAFVSITM QNIGAMSSYL FIIKYELPEV IRAFMGLEEN TGEWYLNGNY LIIFVSVGII LPLSLLKNLG YLGYTSGFSL TCMVFFVSVV IYKKFQIPCP LPVLDHSVGN LSFNNTLPMH VVMLPNNSES SDVNFMMDYT HRNPAGLDEN QAKGSLHDSG VEYEAHSDDK CEPKYFVFNS RTAYAIPILV FAFVCHPEVL PIYSELKDRS RRKMQTVSNI SITGMLVMYL LAALFGYLTF YGEVEDELLH AYSKVYTLDI PLLMVRLAVL VAVTLTVPIV LFPIRTSVIT LLFPKRPFSW IRHFLIAAVL IALNNVLVIL VPTIKYIFGF IGASSATMLI FILPAVFYLK LVKKETFRSP QKVGALIFLV VGIFFMIGSM ALIIIDWIYD PPNSKHH
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