About BLOC-1-related complex subunit 5
BLOC-1-related complex subunit 5 (BORCS5) is a protein
from Homo sapiens identified by UniProt accession
Q969J3, 196 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | BLOC-1-related complex subunit 5 |
|---|
| UniProt accession | Q969J3 |
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| Gene | BORCS5 |
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| Organism | Homo sapiens |
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| Length | 196 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.36
- lymphocyte percentage of leukocytes · score 0.36
- neutrophil percentage of leukocytes · score 0.35
- aspartate aminotransferase measurement · score 0.33
- bone density · score 0.26
- urate measurement · score 0.26
- Global developmental delay · score 0.26
- polymicrogyria · score 0.26
- Microcephaly · score 0.26
- Seizure · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969J3-F1 | alphafold | PREDICTED | 79.71 | — |
Amino-acid sequence (196 residues)
MGSEQSSEAE SRPNDLNSSV TPSPAKHRAK MDDIVVVAQG SQASRNVSND PDVIKLQEIP TFQPLLKGLL SGQTSPTNAK LEKLDSQQVL QLCLRYQDHL HQCAEAVAFD QNALVKRIKE MDLSVETLFS FMQERQKRYA KYAEQIQKVN EMSAILRRIQ MGIDQTVPLL DRLNSMLPEG ERLEPFSMKP DRELRL
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