About Protein MAL2
Protein MAL2 (MAL2) is a protein
from Homo sapiens identified by UniProt accession
Q969L2, 176 residues long.
MolForge cross-references it against 0 known binders and
116 disease associations.
Target properties
| Protein name | Protein MAL2 |
|---|
| UniProt accession | Q969L2 |
|---|
| Gene | MAL2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 176 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (116)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.40
- serum gamma-glutamyl transferase measurement · score 0.39
- osteoprotegerin measurement · score 0.39
- aspartate aminotransferase measurement · score 0.36
- lymphocyte count · score 0.28
- neuroimaging measurement · score 0.28
- brain volume measurement · score 0.28
- eosinophil count · score 0.27
- gallstones · score 0.25
- blood protein measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969L2-F1 | alphafold | PREDICTED | 84.91 | — |
Amino-acid sequence (176 residues)
MSAGGASVPP PPNPAVSFPP PRVTLPAGPD ILRTYSGAFV CLEILFGGLV WILVASSNVP LPLLQGWVMF VSVTAFFFSL LFLGMFLSGM VAQIDANWNF LDFAYHFTVF VFYFGAFLLE AAATSLHDLH CNTTITGQPL LSDNQYNINV AASIFAFMTT ACYGCSLGLA LRRWRP
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