Mitochondrial import receptor subunit TOM40B (TOMM40L)

About Mitochondrial import receptor subunit TOM40B

Mitochondrial import receptor subunit TOM40B (TOMM40L) is a protein from Homo sapiens identified by UniProt accession Q969M1, 308 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Mitochondrial import receptor subunit TOM40B
UniProt accession	Q969M1
Gene	TOMM40L
Organism	Homo sapiens
Length	308 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
hypercholesterolemia, familial, 1 · score 0.33
blood metabolite measurement · score 0.20
bilirubin measurement · score 0.18
platelet count · score 0.12
Red cell distribution width · score 0.12
mean platelet volume · score 0.11
platelet component distribution width · score 0.10
lipoprotein measurement · score 0.08
blood protein measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969M1-F1	alphafold	PREDICTED	90.20	—

Amino-acid sequence (308 residues)

MGNTLGLAPM GTLPRRSPRR EEPLPNPGSF DELHRLCKDV FPAQMEGVKL VVNKVLSSHF QVAHTIHMSA LGLPGYHLHA AYAGDWQLSP TEVFPTVVGD MDSSGSLNAQ VLLLLAERLR AKAVFQTQQA KFLTWQFDGE YRGDDYTATL TLGNPDLIGE SVIMVAHFLQ SLTHRLVLGG ELVYHRRPGE EGAILTLAGK YSAVHWVATL NVGSGGAHAS YYHRANEQVQ VGVEFEANTR LQDTTFSFGY HLTLPQANMV FRGLVDSNWC VGAVLEKKMP PLPVTLALGA FLNHWRNRFH CGFSITVG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards