About Gap junction alpha-10 protein
Gap junction alpha-10 protein (GJA10) is a protein
from Homo sapiens identified by UniProt accession
Q969M2, 543 residues long.
MolForge cross-references it against 0 known binders and
131 disease associations.
Target properties
| Protein name | Gap junction alpha-10 protein |
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| UniProt accession | Q969M2 |
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| Gene | GJA10 |
|---|
| Organism | Homo sapiens |
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| Length | 543 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969M2-F1 | alphafold | PREDICTED | 58.11 | — |
Amino-acid sequence (543 residues)
MGDWNLLGGI LEEVHSHSTI VGKIWLTILF IFRMLVLRVA AEDVWDDEQS AFACNTRQPG CNNICYDDAF PISLIRFWVL QIIFVSSPSL VYMGHALYRL RAFEKDRQRK KSHLRAQMEN PDLDLEEQQR IDRELRRLEE QKRIHKVPLK GCLLRTYVLH ILTRSVLEVG FMIGQYILYG FQMHPLYKCT QPPCPNAVDC FVSRPTEKTI FMLFMHSIAA ISLLLNILEI FHLGIRKIMR TLYKKSSSEG IEDETGPPFH LKKYSVAQQC MICSSLPERI SPLQANNQQQ VIRVNVPKSK TMWQIPQPRQ LEVDPSNGKK DWSEKDQHSG QLHVHSPCPW AGSAGNQHLG QQSDHSSFGL QNTMSQSWLG TTTAPRNCPS FAVGTWEQSQ DPEPSGEPLT DLHSHCRDSE GSMRESGVWI DRSRPGSRKA SFLSRLLSEK RHLHSDSGSS GSRNSSCLDF PHWENSPSPL PSVTGHRTSM VRQAALPIME LSQELFHSGC FLFPFFLPGV CMYVCVDREA DGGGDYLWRD KIIHSIHSVK FNS
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