F-box only protein 32 (FBXO32)

About F-box only protein 32

F-box only protein 32 (FBXO32) is a protein from Homo sapiens identified by UniProt accession Q969P5, 355 residues long. MolForge cross-references it against 0 known binders and 196 disease associations.

Target properties

Protein name	F-box only protein 32
UniProt accession	Q969P5
Gene	FBXO32
Organism	Homo sapiens
Length	355 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (196)

Diseases linked to this target (Open Targets).

atrial fibrillation · score 0.40
electrocardiography · score 0.40
intraocular pressure measurement · score 0.37
open-angle glaucoma · score 0.37
breast carcinoma · score 0.32
heel bone mineral density · score 0.32
glaucoma · score 0.31
aortic measurement · score 0.30
carotid artery intima media thickness · score 0.29
pulse pressure measurement · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969P5-F1	alphafold	PREDICTED	79.94	—

Amino-acid sequence (355 residues)

MPFLGQDWRS PGQNWVKTAD GWKRFLDEKS GSFVSDLSSY CNKEVYNKEN LFNSLNYDVA AKKRKKDMLN SKTKTQYFHQ EKWIYVHKGS TKERHGYCTL GEAFNRLDFS TAILDSRRFN YVVRLLELIA KSQLTSLSGI AQKNFMNILE KVVLKVLEDQ QNIRLIRELL QTLYTSLCTL VQRVGKSVLV GNINMWVYRM ETILHWQQQL NNIQITRPAF KGLTFTDLPL CLQLNIMQRL SDGRDLVSLG QAAPDLHVLS EDRLLWKKLC QYHFSERQIR KRLILSDKGQ LDWKKMYFKL VRCYPRKEQY GDTLQLCKHC HILSWKGTDH PCTANNPESC SVSLSPQDFI NLFKF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards