ADP-ribosylation factor-like protein 11 (ARL11)

About ADP-ribosylation factor-like protein 11

ADP-ribosylation factor-like protein 11 (ARL11) is a protein from Homo sapiens identified by UniProt accession Q969Q4, 196 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	ADP-ribosylation factor-like protein 11
UniProt accession	Q969Q4
Gene	ARL11
Organism	Homo sapiens
Length	196 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (48)

Diseases linked to this target (Open Targets).

platelet count · score 0.19
total cholesterol measurement · score 0.12
total blood protein measurement · score 0.10
breast cancer · score 0.08
schizophrenia · score 0.07
systemic lupus erythematosus · score 0.07
body height · score 0.04
Myopia · score 0.04
age at onset · score 0.04
skin basal cell carcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969Q4-F1	alphafold	PREDICTED	87.59	—

Amino-acid sequence (196 residues)

MGSVNSRGHK AEAQVVMMGL DSAGKTTLLY KLKGHQLVET LPTVGFNVEP LKAPGHVSLT LWDVGGQAPL RASWKDYLEG TDILVYVLDS TDEARLPESA AELTEVLNDP NMAGVPFLVL ANKQEAPDAL PLLKIRNRLS LERFQDHCWE LRGCSALTGE GLPEALQSLW SLLKSRSCMC LQARAHGAER GDSKRS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards