About KICSTOR complex protein ITFG2
KICSTOR complex protein ITFG2 (ITFG2) is a protein
from Homo sapiens identified by UniProt accession
Q969R8, 447 residues long.
MolForge cross-references it against 0 known binders and
211 disease associations.
Target properties
| Protein name | KICSTOR complex protein ITFG2 |
|---|
| UniProt accession | Q969R8 |
|---|
| Gene | ITFG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 447 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (211)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- Intellectual disability · score 0.19
- Ataxia · score 0.18
- Neurodevelopmental abnormality · score 0.18
- Developmental regression · score 0.18
- mean corpuscular volume · score 0.15
- hematocrit · score 0.07
- common variable immunodeficiency · score 0.07
- isolated agammaglobulinemia · score 0.07
- hemoglobin measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969R8-F1 | alphafold | PREDICTED | 86.41 | — |
Amino-acid sequence (447 residues)
MRSVSYVQRV ALEFSGSLFP HAICLGDVDN DTLNELVVGD TSGKVSVYKN DDSRPWLTCS CQGMLTCVGV GDVCNKGKNL LVAVSAEGWF HLFDLTPAKV LDASGHHETL IGEEQRPVFK QHIPANTKVM LISDIDGDGC RELVVGYTDR VVRAFRWEEL GEGPEHLTGQ LVSLKKWMLE GQVDSLSVTL GPLGLPELMV SQPGCAYAIL LCTWKKDTGS PPASEGPTDG SRETPAARDV VLHQTSGRIH NKNVSTHLIG NIKQGHGTES SGSGLFALCT LDGTLKLMEE MEEADKLLWS VQVDHQLFAL EKLDVTGNGH EEVVACAWDG QTYIIDHNRT VVRFQVDENI RAFCAGLYAC KEGRNSPCLV YVTFNQKIYV YWEVQLERME STNLVKLLET KPEYHSLLQE LGVDPDDLPV TRALLHQTLY HPDQPPQCAP SSLQDPT
Explore KICSTOR complex protein ITFG2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets