About Ubiquitin-conjugating enzyme E2 E3
Ubiquitin-conjugating enzyme E2 E3 (UBE2E3) is a protein
from Homo sapiens identified by UniProt accession
Q969T4, 207 residues long.
MolForge cross-references it against 0 known binders and
188 disease associations.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 E3 |
|---|
| UniProt accession | Q969T4 |
|---|
| Gene | UBE2E3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 207 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (188)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.47
- mean corpuscular volume · score 0.46
- erythrocyte count · score 0.45
- leukocyte count · score 0.45
- heel bone mineral density · score 0.44
- alkaline phosphatase measurement · score 0.43
- hematocrit · score 0.41
- eosinophil count · score 0.41
- hemoglobin measurement · score 0.40
- basophil count · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969T4-F1 | alphafold | PREDICTED | 85.15 | — |
Amino-acid sequence (207 residues)
MSSDRQRSDD ESPSTSSGSS DADQRDPAAP EPEEQEERKP SATQQKKNTK LSSKTTAKLS TSAKRIQKEL AEITLDPPPN CSAGPKGDNI YEWRSTILGP PGSVYEGGVF FLDITFSSDY PFKPPKVTFR TRIYHCNINS QGVICLDILK DNWSPALTIS KVLLSICSLL TDCNPADPLV GSIATQYLTN RAEHDRIARQ WTKRYAT
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