About Proteasome assembly chaperone 2
Proteasome assembly chaperone 2 (PSMG2) is a protein
from Homo sapiens identified by UniProt accession
Q969U7, 264 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Proteasome assembly chaperone 2 |
|---|
| UniProt accession | Q969U7 |
|---|
| Gene | PSMG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 264 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- proteasome-associated autoinflammatory syndrome 4 · score 0.53
- Short stature · score 0.30
- pulse pressure measurement · score 0.18
- hemoglobin measurement · score 0.07
- response to vaccine · score 0.07
- erythrocyte count · score 0.06
- diabetic nephropathy · score 0.06
- red blood cell density measurement · score 0.06
- hematocrit · score 0.05
- triple-negative breast cancer · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969U7-F1 | alphafold | PREDICTED | 92.50 | — |
Amino-acid sequence (264 residues)
MFVPCGESAP DLAGFTLLMP AVSVGNVGQL AMDLIISTLN MSKIGYFYTD CLVPMVGNNP YATTEGNSTE LSINAEVYSL PSRKLVALQL RSIFIKYKSK PFCEKLLSWV KSSGCARVIV LSSSHSYQRN DLQLRSTPFR YLLTPSMQKS VQNKIKSLNW EEMEKSRCIP EIDDSEFCIR IPGGGITKTL YDESCSKEIQ MAVLLKFVSE GDNIPDALGL VEYLNEWLQI LKPLSDDPTV SASRWKIPSS WRLLFGSGLP PALF
Explore Proteasome assembly chaperone 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets