Palmitoyltransferase ZDHHC16 (ZDHHC16)

About Palmitoyltransferase ZDHHC16

Palmitoyltransferase ZDHHC16 (ZDHHC16) is a protein from Homo sapiens identified by UniProt accession Q969W1, 377 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.

Target properties

Protein name	Palmitoyltransferase ZDHHC16
UniProt accession	Q969W1
Gene	ZDHHC16
Organism	Homo sapiens
Length	377 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (71)

Diseases linked to this target (Open Targets).

serum alanine aminotransferase measurement · score 0.09
serum gamma-glutamyl transferase measurement · score 0.08
BMI-adjusted waist circumference · score 0.07
hypertrophic cardiomyopathy · score 0.06
Arrhythmogenic right ventricular dysplasia · score 0.04
cardiomyopathy, dilated, 2G · score 0.04
dilated cardiomyopathy 1AA · score 0.04
myopathy, distal, 7, adult-onset, X-linked · score 0.04
melorheostosis · score 0.04
hypertrophic cardiomyopathy 6 · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969W1-F1	alphafold	PREDICTED	87.67	—

Amino-acid sequence (377 residues)

MRGQRSLLLG PARLCLRLLL LLGYRRRCPP LLRGLVQRWR YGKVCLRSLL YNSFGGSDTA VDAAFEPVYW LVDNVIRWFG VVFVVLVIVL TGSIVAIAYL CVLPLILRTY SVPRLCWHFF YSHWNLILIV FHYYQAITTP PGYPPQGRND IATVSICKKC IYPKPARTHH CSICNRCVLK MDHHCPWLNN CVGHYNHRYF FSFCFFMTLG CVYCSYGSWD LFREAYAAIE KMKQLDKNKL QAVANQTYHQ TPPPTFSFRE RMTHKSLVYL WFLCSSVALA LGALTVWHAV LISRGETSIE RHINKKERRR LQAKGRVFRN PYNYGCLDNW KVFLGVDTGR HWLTRVLLPS SHLPHGNGMS WEPPPWVTAH SASVMAV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards