About Protein VCF1
Protein VCF1 (VCF1) is a protein
from Homo sapiens identified by UniProt accession
Q969W3, 186 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Protein VCF1 |
|---|
| UniProt accession | Q969W3 |
|---|
| Gene | VCF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 186 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (37)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.31
- erythrocyte count · score 0.28
- mean corpuscular hemoglobin · score 0.28
- Red cell distribution width · score 0.28
- mean corpuscular hemoglobin concentration · score 0.27
- reticulocyte count · score 0.22
- mean reticulocyte volume · score 0.21
- COG1-congenital disorder of glycosylation · score 0.20
- genetic disorder · score 0.17
- jaw fracture · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969W3-F1 | alphafold | PREDICTED | 61.77 | — |
Amino-acid sequence (186 residues)
MGGRGADAGS SGGTGPTEGY SPPAASTRAA ARAKARGGGR GGRRNTTPSV PSLRGAAPRS FHPPAAMSER LRPRKRRRNG NEEDNHLPPQ TKRSSRNPVF QDSWDTESSG SDSGGSSSSS SSSINSPDRA SGPEGSLSQT MAGSSPNTPQ PVPEQSALCQ GLYFHINQTL REAHFHSLQH RGRPLT
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