RILP-like protein 2 (RILPL2)

Homo sapiens — UniProt Q969X0

Gene: RILPL2Homo sapiensSwissProt reviewed

About RILP-like protein 2

RILP-like protein 2 (RILPL2) is a protein from Homo sapiens identified by UniProt accession Q969X0, 211 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.

Target properties

Protein nameRILP-like protein 2
UniProt accessionQ969X0
GeneRILPL2
OrganismHomo sapiens
Length211 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (91)

Diseases linked to this target (Open Targets).

  • BMI-adjusted waist-hip ratio · score 0.35
  • BMI-adjusted waist circumference · score 0.32
  • neurodegenerative disease · score 0.31
  • self reported educational attainment · score 0.30
  • body height · score 0.27
  • appendicular lean mass · score 0.21
  • osteoarthritis, knee · score 0.12
  • osteoarthritis, hip · score 0.10
  • non-small cell lung carcinoma · score 0.08
  • lean body mass · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q969X0-F1alphafoldPREDICTED77.19—

Amino-acid sequence (211 residues)

MEEPPVREEE EEEGEEDEER DEVGPEGALG KSPFQLTAED VYDISYLLGR ELMALGSDPR VTQLQFKVVR VLEMLEALVN EGSLALEELK MERDHLRKEV EGLRRQSPPA SGEVNLGPNK MVVDLTDPNR PRFTLQELRD VLQERNKLKS QLLVVQEELQ CYKSGLIPPR EGPGGRREKD AVVTSAKNAG RNKEEKTIIK KLFFFRSGKQ T

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Quick facts

UniProtQ969X0
GeneRILPL2
OrganismHomo sapiens
Length211
Binders0
Diseases91
View on UniProt