About RILP-like protein 2
RILP-like protein 2 (RILPL2) is a protein
from Homo sapiens identified by UniProt accession
Q969X0, 211 residues long.
MolForge cross-references it against 0 known binders and
91 disease associations.
Target properties
| Protein name | RILP-like protein 2 |
| UniProt accession | Q969X0 |
| Gene | RILPL2 |
| Organism | Homo sapiens |
| Length | 211 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.35
- BMI-adjusted waist circumference · score 0.32
- neurodegenerative disease · score 0.31
- self reported educational attainment · score 0.30
- body height · score 0.27
- appendicular lean mass · score 0.21
- osteoarthritis, knee · score 0.12
- osteoarthritis, hip · score 0.10
- non-small cell lung carcinoma · score 0.08
- lean body mass · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q969X0-F1 | alphafold | PREDICTED | 77.19 | — |
Amino-acid sequence (211 residues)
MEEPPVREEE EEEGEEDEER DEVGPEGALG KSPFQLTAED VYDISYLLGR ELMALGSDPR VTQLQFKVVR VLEMLEALVN EGSLALEELK MERDHLRKEV EGLRRQSPPA SGEVNLGPNK MVVDLTDPNR PRFTLQELRD VLQERNKLKS QLLVVQEELQ CYKSGLIPPR EGPGGRREKD AVVTSAKNAG RNKEEKTIIK KLFFFRSGKQ T
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