NXPE family member 3 (NXPE3)

About NXPE family member 3

NXPE family member 3 (NXPE3) is a protein from Homo sapiens identified by UniProt accession Q969Y0, 559 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	NXPE family member 3
UniProt accession	Q969Y0
Gene	NXPE3
Organism	Homo sapiens
Length	559 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

COVID-19 · score 0.18
psoriasis · score 0.18
psoriasis vulgaris · score 0.14
serum non-albumin protein measurement · score 0.14
PHF-tau measurement · score 0.13
type 2 diabetes mellitus · score 0.13
peritonsillar abscess · score 0.10
C-reactive protein measurement · score 0.04
eosinophil count · score 0.04
anxiety disorder · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q969Y0-F1	alphafold	PREDICTED	89.58	—

Amino-acid sequence (559 residues)

MWTNFFKLRL FCCLLAVLMV VVLVINVTQV EYLDHETVSA TFIDSSGQFV SSQVTGISRN PYCGYDQQTL SSQERMEEDS LLAALHRQVP DVGPVPFVKS TDPSSSYFVI LNSAAFFKVG SQLEVLVHVQ DFQRKPKKYG GDYLQARIHS LKLQAGAVGR VVDYQNGFYK VFFTLLWPGK VKVSVSLVHP SEGIRVLQRL QEDKPDRVYF KSLFRSGRIS ETTECNVCLP GNLPLCNFTD LYTGEPWFCF KPKKLPCSSR ITHFKGGYLK GLLTAAESAF FQSGVNIKMP VNSSGPDWVT VIPRRIKETN SLELSQGSGT FPSGYYYKDQ WRPRKFKMRQ FNDPDNITEC LQRKVVHLFG DSTIRQWFEY LTTFVPDLVE FNLGSPKNVG PFLAVDQKHN ILLKYRCHGP PIRFTTVFSN ELHYVANELN GIVGGKNTVV AIAVWSHFST FPLEVYIRRL RNIRRAVVRL LDRSPKTVVV IRTANAQELG PEVSLFNSDW YNFQLDTILR RMFSGVGVYL VDAWEMTLAH YLPHKLHPDE VIVKNQLDMF LSFVCPLET

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards