About 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial
5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial (GTPBP3) is a protein
from Homo sapiens identified by UniProt accession
Q969Y2, 492 residues long.
MolForge cross-references it against 0 known binders and
31 disease associations.
Target properties
| Protein name | 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial |
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| UniProt accession | Q969Y2 |
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| Gene | GTPBP3 |
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| Organism | Homo sapiens |
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| Length | 492 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
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| AF-Q969Y2-F1 | alphafold | PREDICTED | 81.96 | — |
Amino-acid sequence (492 residues)
MWRGLWTLAA QAARGPRRLC TRRSSGAPAP GSGATIFALS SGQGRCGIAV IRTSGPASGH ALRILTAPRD LPLARHASLR LLSDPRSGEP LDRALVLWFP GPQSFTGEDC VEFHVHGGPA VVSGVLQALG SVPGLRPAEA GEFTRRAFAN GKLNLTEVEG LADLIHAETE AQRRQALRQL DGELGHLCRG WAETLTKALA HVEAYIDFGE DDNLEEGVLE QADIEVRALQ VALGAHLRDA RRGQRLRSGV HVVVTGPPNA GKSSLVNLLS RKPVSIVSPE PGTTRDVLET PVDLAGFPVL LSDTAGLREG VGPVEQEGVR RARERLEQAD LILAMLDASD LASPSSCNFL ATVVASVGAQ SPSDSSQRLL LVLNKSDLLS PEGPGPGPDL PPHLLLSCLT GEGLDGLLEA LRKELAAVCG DPSTDPPLLT RARHQHHLQG CLDALGHYKQ SKDLALAAEA LRVARGHLTR LTGGGGTEEI LDIIFQDFCV GK
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