About Tumor necrosis factor receptor superfamily member 19L
Tumor necrosis factor receptor superfamily member 19L (RELT) is a protein
from Homo sapiens identified by UniProt accession
Q969Z4, 430 residues long.
MolForge cross-references it against 0 known binders and
115 disease associations.
Target properties
| Protein name | Tumor necrosis factor receptor superfamily member 19L |
|---|
| UniProt accession | Q969Z4 |
|---|
| Gene | RELT |
|---|
| Organism | Homo sapiens |
|---|
| Length | 430 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (115)
Diseases linked to this target (Open Targets).
- amelogenesis imperfecta · score 0.52
- Hypoplastic amelogenesis imperfecta · score 0.40
- genetic disorder · score 0.19
- blood protein measurement · score 0.18
- Hypomaturation amelogenesis imperfecta · score 0.11
- forced expiratory volume · score 0.10
- Varicose veins · score 0.09
- tumor necrosis factor receptor superfamily member 19L measurement · score 0.09
- diastolic blood pressure · score 0.09
- amelogenesis imperfecta hypomaturation type 2A4 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q969Z4-F1 | alphafold | PREDICTED | 62.85 | — |
Amino-acid sequence (430 residues)
MKPSLLCRPL SCFLMLLPWP LATLTSTTLW QCPPGEEPDL DPGQGTLCRP CPPGTFSAAW GSSPCQPHAR CSLWRRLEAQ VGMATRDTLC GDCWPGWFGP WGVPRVPCQP CSWAPLGTHG CDEWGRRARR GVEVAAGASS GGETRQPGNG TRAGGPEETA AQYAVIAIVP VFCLMGLLGI LVCNLLKRKG YHCTAHKEVG PGPGGGGSGI NPAYRTEDAN EDTIGVLVRL ITEKKENAAA LEELLKEYHS KQLVQTSHRP VSKLPPAPPN VPHICPHRHH LHTVQGLASL SGPCCSRCSQ KKWPEVLLSP EAVAATTPVP SLLPNPTRVP KAGAKAGRQG EITILSVGRF RVARIPEQRT SSMVSEVKTI TEAGPSWGDL PDSPQPGLPP EQQALLGSGG SRTKWLKPPA ENKAEENRYV VRLSESNLVI
Explore Tumor necrosis factor receptor superfamily member 19L with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets