PAT complex subunit CCDC47 (CCDC47)

About PAT complex subunit CCDC47

PAT complex subunit CCDC47 (CCDC47) is a protein from Homo sapiens identified by UniProt accession Q96A33, 483 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein name	PAT complex subunit CCDC47
UniProt accession	Q96A33
Gene	CCDC47
Organism	Homo sapiens
Length	483 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (53)

Diseases linked to this target (Open Targets).

trichohepatoneurodevelopmental syndrome · score 0.67
Woolly hair · score 0.37
Abnormality of the liver · score 0.37
Global developmental delay · score 0.37
Intellectual disability · score 0.37
body height · score 0.17
body fat percentage · score 0.17
IGF-1 measurement · score 0.16
PR interval · score 0.13
BMI-adjusted waist circumference · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96A33-F1	alphafold	PREDICTED	76.83	—

Amino-acid sequence (483 residues)

MKAFHTFCVV LLVFGSVSEA KFDDFEDEED IVEYDDNDFA EFEDVMEDSV TESPQRVIIT EDDEDETTVE LEGQDENQEG DFEDADTQEG DTESEPYDDE EFEGYEDKPD TSSSKNKDPI TIVDVPAHLQ NSWESYYLEI LMVTGLLAYI MNYIIGKNKN SRLAQAWFNT HRELLESNFT LVGDDGTNKE ATSTGKLNQE NEHIYNLWCS GRVCCEGMLI QLRFLKRQDL LNVLARMMRP VSDQVQIKVT MNDEDMDTYV FAVGTRKALV RLQKEMQDLS EFCSDKPKSG AKYGLPDSLA ILSEMGEVTD GMMDTKMVHF LTHYADKIES VHFSDQFSGP KIMQEEGQPL KLPDTKRTLL FTFNVPGSGN TYPKDMEALL PLMNMVIYSI DKAKKFRLNR EGKQKADKNR ARVEENFLKL THVQRQEAAQ SRREEKKRAE KERIMNEEDP EKQRRLEEAA LRREQKKLEK KQMKMKQIKV KAM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards