Protein mago nashi homolog 2 (MAGOHB)

About Protein mago nashi homolog 2

Protein mago nashi homolog 2 (MAGOHB) is a protein from Homo sapiens identified by UniProt accession Q96A72, 148 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Protein mago nashi homolog 2
UniProt accession	Q96A72
Gene	MAGOHB
Organism	Homo sapiens
Length	148 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
dentures · score 0.12
cardiomyopathy · score 0.12
dental caries · score 0.10
cutaneous melanoma · score 0.07
melanoma · score 0.05
neoplasm · score 0.04
cancer · score 0.04
glioblastoma multiforme · score 0.03
susceptibility to familial cutaneous melanoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96A72-F1	alphafold	PREDICTED	93.18	—

Amino-acid sequence (148 residues)

MAVASDFYLR YYVGHKGKFG HEFLEFEFRP DGKLRYANNS NYKNDVMIRK EAYVHKSVME ELKRIIDDSE ITKEDDALWP PPDRVGRQEL EIVIGDEHIS FTTSKIGSLI DVNQSKDPEG LRVFYYLVQD LKCLVFSLIG LHFKIKPI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards