Collagen alpha-1(XXVI) chain (COL26A1)

About Collagen alpha-1(XXVI) chain

Collagen alpha-1(XXVI) chain (COL26A1) is a protein from Homo sapiens identified by UniProt accession Q96A83, 441 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein name	Collagen alpha-1(XXVI) chain
UniProt accession	Q96A83
Gene	COL26A1
Organism	Homo sapiens
Length	441 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (62)

Diseases linked to this target (Open Targets).

cortical thickness · score 0.40
neuroimaging measurement · score 0.38
brain measurement · score 0.36
cortical surface area measurement · score 0.32
response to antidepressant · score 0.31
intraocular pressure measurement · score 0.30
mental or behavioural disorder · score 0.27
hemoglobin measurement · score 0.26
breast adenocarcinoma · score 0.26
lung adenocarcinoma · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96A83-F1	alphafold	PREDICTED	59.65	—

Amino-acid sequence (441 residues)

MKLALLLPWA CCCLCGSALA TGFLYPFSAA ALQQHGYPEP GAGSPGSGYA SRRHWCHHTV TRTVSCQVQN GSETVVQRVY QSCRWPGPCA NLVSYRTLIR PTYRVSYRTV TVLEWRCCPG FTGSNCDEEC MNCTRLSDMS ERLTTLEAKV LLLEAAERPS SPDNDLPAPE STPPTWNEDF LPDAIPLAHP VPRQRRPTGP AGPPGQTGPP GPAGPPGSKG DRGQTGEKGP AGPPGLLGPP GPRGLPGEMG RPGPPGPPGP AGNPGPSPNS PQGALYSLQP PTDKDNGDSR LASAIVDTVL AGVPGPRGPP GPPGPPGPRG PPGPPGTPGS QGLAGERGTV GPSGEPGVKG EEGEKAATAE GEGVQQLREA LKILAERVLI LEHMIGIHDP LASPEGGSGQ DAALRANLKM KRGGAQPDGV LAALLGPDPG QKSVDQASSR K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards