Protein N-terminal asparagine amidohydrolase (NTAN1)

About Protein N-terminal asparagine amidohydrolase

Protein N-terminal asparagine amidohydrolase (NTAN1) is a protein from Homo sapiens identified by UniProt accession Q96AB6, 310 residues long. MolForge cross-references it against 0 known binders and 138 disease associations.

Target properties

Protein name	Protein N-terminal asparagine amidohydrolase
UniProt accession	Q96AB6
Gene	NTAN1
Organism	Homo sapiens
Length	310 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (138)

Diseases linked to this target (Open Targets).

phosphatidylcholine measurement · score 0.45
triglyceride measurement · score 0.43
body height · score 0.41
cholesteryl ester 20:3 measurement · score 0.39
blood metabolite measurement · score 0.39
high density lipoprotein cholesterol measurement · score 0.37
sex hormone-binding globulin measurement · score 0.37
omega-6 polyunsaturated fatty acid measurement · score 0.37
lean body mass · score 0.36
body mass index · score 0.36

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96AB6-F1	alphafold	PREDICTED	95.61	—

Amino-acid sequence (310 residues)

MPLLVEGRRV RLPQSAGDLV RAHPPLEERA RLLRGQSVQQ VGPQGLLYVQ QRELAVTSPK DGSISILGSD DATTCHIVVL RHTGNGATCL THCDGTDTKA EVPLIMNSIK SFSDHAQCGR LEVHLVGGFS DDRQLSQKLT HQLLSEFDRQ EDDIHLVTLC VTELNDREEN ENHFPVIYGI AVNIKTAEIY RASFQDRGPE EQLRAARTLA GGPMISIYDA ETEQLRIGPY SWTPFPHVDF WLHQDDKQIL ENLSTSPLAE PPHFVEHIRS TLMFLKKHPS PAHTLFSGNK ALLYKKNEDG LWEKISSPGS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards