About Kinesin-like protein KIFC2
Kinesin-like protein KIFC2 (KIFC2) is a protein
from Homo sapiens identified by UniProt accession
Q96AC6, 838 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Kinesin-like protein KIFC2 |
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| UniProt accession | Q96AC6 |
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| Gene | KIFC2 |
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| Organism | Homo sapiens |
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| Length | 838 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (33)
Diseases linked to this target (Open Targets).
- serum alanine aminotransferase measurement · score 0.27
- mathematical ability · score 0.26
- self reported educational attainment · score 0.19
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- holoprosencephaly · score 0.18
- breast adenocarcinoma · score 0.18
- cognitive function measurement · score 0.15
- glioblastoma multiforme · score 0.15
- esophageal cancer · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96AC6-F1 | alphafold | PREDICTED | 63.08 | — |
Amino-acid sequence (838 residues)
MYAFYSLLIY IFYSLFRRDG GAAAAAEPGD PAQRARKPRG RRRPDLPAPE LWTELTGLAA SSEPEDGSEG AAEGRAAAVS LEEALLRLAE FLSVQLGAEE SCGGPADLGQ SGEVPSLLTV TSQLLALLAW LRSPRGRQAL LQGTQPAPRV RPPSPDGSTS QEESPSHFTA VPGEPLGDET QGQQPLQLEE DQRAWQRLEQ LILGQLEELK QQLEQQEEEL GRLRLGVGAT DSEKRVQHLT LENEALKQSL SLMRDLLLHW GPGPPIRAPQ EEAEALLELQ GRLQEAQDTT EALRAQLGVQ EVQLQGLQGA LQQLQQETEQ NCRRELQQMH GQLAGLRARM ASLRQGCGDL RGLVSTFTQS CQGSLSEARG QVSWALGALS SGGPGTQLPE GQQGPPAGCP GRLPELKGNI RVLCRLRPGT SSSLVSVEPG PGGTVTTCYR GRHRRFRLDW VFPPDASQEE VFRELEPAVL SCLRGYSVCI FTYGQTGTGK TYSMEGPPED PGIVPRALQS LFREMGAGRQ HRVTLSMVEI YNEAVRDLLA PGPPERLAVR QGPEGQGGIQ VAGLTHWDVP NLETLHQMLK LGRSNRATAA TAMNQRSSRS HALVTLTLRA ASPPRAPGTA GTLHLVDLAG SERARKAGAA GPPRGDPDGA RRLREAQTIN RSLLALGGVM AALRAHRPHV PFRDSQLTRL LQPALGPGTT AVLLLQVGAG AGQVCACRSP PTRARPPAPL ARRSPRGRRI SGRQSAPSSS PTEWVKWSWG QPGAAGSRAP PGRLLPSAPT LRSPGPPAPL RRPLAVLHAP VPTTARARLS RPQRACPSSP GSRPCPWGLR PGLCWQRR
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