About Mas-related G-protein coupled receptor member F
Mas-related G-protein coupled receptor member F (MRGPRF) is a protein
from Homo sapiens identified by UniProt accession
Q96AM1, 343 residues long.
MolForge cross-references it against 0 known binders and
61 disease associations.
Target properties
| Protein name | Mas-related G-protein coupled receptor member F |
|---|
| UniProt accession | Q96AM1 |
|---|
| Gene | MRGPRF |
|---|
| Organism | Homo sapiens |
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| Length | 343 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (61)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.10
- neoplasm · score 0.09
- body height · score 0.08
- lean body mass · score 0.06
- protein measurement · score 0.06
- melanoma · score 0.06
- fat body mass · score 0.05
- body mass index · score 0.04
- hip circumference · score 0.04
- appendicular lean mass · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96AM1-F1 | alphafold | PREDICTED | 79.95 | — |
Amino-acid sequence (343 residues)
MAGNCSWEAH PGNRNKMCPG LSEAPELYSR GFLTIEQIAM LPPPAVMNYI FLLLCLCGLV GNGLVLWFFG FSIKRNPFSI YFLHLASADV GYLFSKAVFS ILNTGGFLGT FADYIRSVCR VLGLCMFLTG VSLLPAVSAE RCASVIFPAW YWRRRPKRLS AVVCALLWVL SLLVTCLHNY FCVFLGRGAP GAACRHMDIF LGILLFLLCC PLMVLPCLAL ILHVECRARR RQRSAKLNHV ILAMVSVFLV SSIYLGIDWF LFWVFQIPAP FPEYVTDLCI CINSSAKPIV YFLAGRDKSQ RLWEPLRVVF QRALRDGAEL GEAGGSTPNT VTMEMQCPPG NAS
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