About Uncharacterized protein KIAA1143
Uncharacterized protein KIAA1143 (KIAA1143) is a protein
from Homo sapiens identified by UniProt accession
Q96AT1, 154 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Uncharacterized protein KIAA1143 |
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| UniProt accession | Q96AT1 |
|---|
| Gene | KIAA1143 |
|---|
| Organism | Homo sapiens |
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| Length | 154 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (11)
Diseases linked to this target (Open Targets).
- pulse pressure measurement · score 0.13
- idiopathic pulmonary fibrosis · score 0.12
- autosomal recessive spondylocostal dysostosis · score 0.07
- cystatin C measurement · score 0.05
- cervical spondylosis · score 0.04
- Prata-Liberal-Goncalves syndrome · score 0.04
- osteomesopyknosis · score 0.04
- depressive symptom measurement · score 0.04
- body fat percentage · score 0.04
- primary basilar invagination · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96AT1-F1 | alphafold | PREDICTED | 72.30 | — |
Amino-acid sequence (154 residues)
MSKRNQVSYV RPAEPAFLAR FKERVGYREG PTVETKRIQP QPPDEDGDHS DKEDEQPQVV VLKKGDLSVE EVMKIKAEIK AAKADEEPTP ADGRIIYRKP VKHPSDEKYS GLTASSKKKK PNEDEVNQDS VKKNSQKQIK NSSLLSFDNE DENE
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