About Ribulose-phosphate 3-epimerase
Ribulose-phosphate 3-epimerase (RPE) is a protein
from Homo sapiens identified by UniProt accession
Q96AT9, 228 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | Ribulose-phosphate 3-epimerase |
|---|
| UniProt accession | Q96AT9 |
|---|
| Gene | RPE |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- lysosomal storage disease · score 0.34
- body height · score 0.34
- blood metabolite measurement · score 0.29
- serum metabolite measurement · score 0.24
- glycine measurement · score 0.23
- creatinine measurement · score 0.19
- glomerular filtration rate · score 0.15
- smoking behaviour measurement · score 0.09
- anxiety · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96AT9-F1 | alphafold | PREDICTED | 96.54 | — |
Amino-acid sequence (228 residues)
MASGCKIGPS ILNSDLANLG AECLRMLDSG ADYLHLDVMD GHFVPNITFG HPVVESLRKQ LGQDPFFDMH MMVSKPEQWV KPMAVAGANQ YTFHLEATEN PGALIKDIRE NGMKVGLAIK PGTSVEYLAP WANQIDMALV MTVEPGFGGQ KFMEDMMPKV HWLRTQFPSL DIEVDGGVGP DTVHKCAEAG ANMIVSGSAI MRSEDPRSVI NLLRNVCSEA AQKRSLDR
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