RAD51-associated protein 1 (RAD51AP1)

About RAD51-associated protein 1

RAD51-associated protein 1 (RAD51AP1) is a protein from Homo sapiens identified by UniProt accession Q96B01, 352 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.

Target properties

Protein name	RAD51-associated protein 1
UniProt accession	Q96B01
Gene	RAD51AP1
Organism	Homo sapiens
Length	352 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (107)

Diseases linked to this target (Open Targets).

phosphate measurement · score 0.33
blood phosphate measurement · score 0.32
alkaline phosphatase measurement · score 0.29
breast adenocarcinoma · score 0.26
low grade glioma · score 0.23
creatinine measurement · score 0.21
lung adenocarcinoma · score 0.17
head and neck squamous cell carcinoma · score 0.11
clear cell renal carcinoma · score 0.10
hepatocellular carcinoma · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96B01-F1	alphafold	PREDICTED	58.64	—

Amino-acid sequence (352 residues)

MVRPVRHKKP VNYSQFDHSD SDDDFVSATV PLNKKSRTAP KELKQDKPKP NLNNLRKEEI PVQEKTPKKR LPEGTFSIPA SAVPCTKMAL DDKLYQRDLE VALALSVKEL PTVTTNVQNS QDKSIEKHGS SKIETMNKSP HISNCSVASD YLDLDKITVE DDVGGVQGKR KAASKAAAQQ RKILLEGSDG DSANDTEPDF APGEDSEDDS DFCESEDNDE DFSMRKSKVK EIKKKEVKVK SPVEKKEKKS KSKCNALVTS VDSAPAAVKS ESQSLPKKVS LSSDTTRKPL EIRSPSAESK KPKWVPPAAS GGSRSSSSPL VVVSVKSPNQ SLRLGLSRLA RVKPLHPNAT ST

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards