Ubiquitin-conjugating enzyme E2 W (UBE2W)

About Ubiquitin-conjugating enzyme E2 W

Ubiquitin-conjugating enzyme E2 W (UBE2W) is a protein from Homo sapiens identified by UniProt accession Q96B02, 151 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

Target properties

Protein name	Ubiquitin-conjugating enzyme E2 W
UniProt accession	Q96B02
Gene	UBE2W
Organism	Homo sapiens
Length	151 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (69)

Diseases linked to this target (Open Targets).

platelet count · score 0.36
body mass index · score 0.36
neurodegenerative disease · score 0.35
mean platelet volume · score 0.35
monocyte count · score 0.19
clear cell renal carcinoma · score 0.18
azoospermia · score 0.05
MODY · score 0.05
partial chromosome Y deletion · score 0.04
neoplasm · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96B02-F1	alphafold	PREDICTED	87.23	—

Amino-acid sequence (151 residues)

MASMQKRLQK ELLALQNDPP PGMTLNEKSV QNSITQWIVD MEGAPGTLYE GEKFQLLFKF SSRYPFDSPQ VMFTGENIPV HPHVYSNGHI CLSILTEDWS PALSVQSVCL SIISMLSSCK EKRRPPDNSF YVRTCNKNPK KTKWWYHDDT C

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards