About Claudin-23
Claudin-23 (CLDN23) is a protein
from Homo sapiens identified by UniProt accession
Q96B33, 292 residues long.
MolForge cross-references it against 0 known binders and
115 disease associations.
Target properties
| Protein name | Claudin-23 |
|---|
| UniProt accession | Q96B33 |
|---|
| Gene | CLDN23 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 292 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (115)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.40
- mathematical ability · score 0.38
- pulse pressure measurement · score 0.36
- risk-taking behaviour · score 0.32
- cystatin C measurement · score 0.31
- serum gamma-glutamyl transferase measurement · score 0.30
- cellulitis · score 0.29
- self reported educational attainment · score 0.27
- urate measurement · score 0.27
- prostate carcinoma · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96B33-F1 | alphafold | PREDICTED | 76.99 | — |
Amino-acid sequence (292 residues)
MRTPVVMTLG MVLAPCGLLL NLTGTLAPGW RLVKGFLNQP VDVELYQGLW DMCREQSSRE RECGQTDQWG YFEAQPVLVA RALMVTSLAA TVLGLLLASL GVRCWQDEPN FVLAGLSGVV LFVAGLLGLI PVSWYNHFLG DRDVLPAPAS PVTVQVSYSL VLGYLGSCLL LLGGFSLALS FAPWCDERCR RRRKGPSAGP RRSSVSTIQV EWPEPDLAPA IKYYSDGQHR PPPAQHRKPK PKPKVGFPMP RPRPKAYTNS VDVLDGEGWE SQDAPSCSTH PCDSSLPCDS DL
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