About Zinc finger protein 428
Zinc finger protein 428 (ZNF428) is a protein
from Homo sapiens identified by UniProt accession
Q96B54, 188 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Zinc finger protein 428 |
|---|
| UniProt accession | Q96B54 |
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| Gene | ZNF428 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 188 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- appendicular lean mass · score 0.05
- forced expiratory volume · score 0.05
- neutrophil count · score 0.03
- leukocyte count · score 0.03
- basophil count · score 0.03
- neutrophil percentage of leukocytes · score 0.03
- lymphocyte count · score 0.03
- monocyte percentage of leukocytes · score 0.03
- lymphocyte percentage of leukocytes · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96B54-F1 | alphafold | PREDICTED | 61.36 | — |
Amino-acid sequence (188 residues)
MTETREPAET GGYASLEEDD EDLSPGPEHS SDSEYTLSEP DSEEEEDEEE EEEETTDDPE YDPGYKVKQR LGGGRGGPSR RAPRAAQPPA QPCQLCGRSP LGEAPPGTPP CRLCCPATAP QEAPAPEGRA LGEEEEEPPR AGEGRPAGRE EEEEEEEEGT YHCTECEDSF DNLGELHGHF MLHARGEV
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