About Lipid droplet assembly factor 1
Lipid droplet assembly factor 1 (LDAF1) is a protein
from Homo sapiens identified by UniProt accession
Q96B96, 161 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Lipid droplet assembly factor 1 |
|---|
| UniProt accession | Q96B96 |
|---|
| Gene | LDAF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 161 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- electroencephalogram measurement · score 0.11
- attention deficit hyperactivity disorder · score 0.09
- systolic blood pressure · score 0.08
- attention deficit-hyperactivity disorder 8 · score 0.07
- schizophrenia 15 · score 0.07
- total blood protein measurement · score 0.07
- creatinine measurement · score 0.06
- diastolic blood pressure · score 0.06
- urate measurement · score 0.06
- cystatin C measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96B96-F1 | alphafold | PREDICTED | 80.02 | — |
Amino-acid sequence (161 residues)
MAKEEPQSIS RDLQELQKKL SLLIDSFQNN SKVVAFMKSP VGQYLDSHPF LAFTLLVFIV MSAVPVGFFL LIVVLTTLAA LLGVIILEGL VISVGGFSLL CILCGLGFVS LAMSGMMIAS YVVVSSLISC WFSPRPLTQQ NTSCDFLPAM KSAEFEGLYQ E
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