About SKA complex subunit 1
SKA complex subunit 1 (SKA1) is a protein
from Homo sapiens identified by UniProt accession
Q96BD8, 255 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | SKA complex subunit 1 |
|---|
| UniProt accession | Q96BD8 |
|---|
| Gene | SKA1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 255 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.18
- hepatocellular carcinoma · score 0.12
- nonpapillary renal cell carcinoma · score 0.09
- breast cancer · score 0.08
- non-small cell lung carcinoma · score 0.08
- renal cell carcinoma · score 0.08
- lung adenocarcinoma · score 0.07
- neoplasm · score 0.07
- papillary thyroid carcinoma · score 0.07
- 3-hydroxy-1-methylpropylmercapturic acid measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96BD8-F1 | alphafold | PREDICTED | 85.38 | — |
Amino-acid sequence (255 residues)
MASSDLEQLC SHVNEKIGNI KKTLSLRNCG QEPTLKTVLN KIGDEIIVIN ELLNKLELEI QYQEQTNNSL KELCESLEED YKDIEHLKEN VPSHLPQVTV TQSCVKGSDL DPEEPIKVEE PEPVKKPPKE QRSIKEMPFI TCDEFNGVPS YMKSRLTYNQ INDVIKEINK AVISKYKILH QPKKSMNSVT RNLYHRFIDE ETKDTKGRYF IVEADIKEFT TLKADKKFHV LLNILRHCRR LSEVRGGGLT RYVIT
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